Creatinine Clearance & eGFR Kidney Calculator
Calculate Cockcroft-Gault Creatinine Clearance (CrCl) for pharmacology drug dosing and 2021 race-free CKD-EPI eGFR for Chronic Kidney Disease staging.
Calculated Results
Frequently Asked Questions
What is the Cockcroft-Gault equation for Creatinine Clearance?
Formulated in 1976, Cockcroft-Gault estimates renal creatinine clearance: CrCl = [(140 - Age) × Weight in kg] / (72 × Serum Creatinine). For females, multiply the result by 0.85 to account for lower average muscular mass.
What is the difference between CrCl and eGFR?
The FDA traditionally uses Cockcroft-Gault CrCl (in mL/min) for pharmaceutical drug dosing adjustments (antibiotics, chemotherapy, anticoagulants). Nephrologists use CKD-EPI eGFR (in mL/min/1.73m²) to officially stage chronic kidney disease.
What are the 5 clinical stages of Chronic Kidney Disease (CKD)?
Stage 1: eGFR ≥ 90 (Normal/High); Stage 2: eGFR 60–89 (Mild reduction); Stage 3a/3b: eGFR 30–59 (Moderate reduction); Stage 4: eGFR 15–29 (Severe reduction); Stage 5: eGFR < 15 (Kidney Failure / Dialysis).
Why was race removed from the 2021 CKD-EPI equation?
In 2021, the National Kidney Foundation and American Society of Nephrology published a revised race-free CKD-EPI equation, eliminating historical race-based coefficients to ensure equitable and unbiased clinical diagnosis.